What is ADAKVEO® (crizanlizumab-tmca)?
ADAKVEO is used
- in people 16 years of age and older who have sickle cell disease
- to help reduce how often certain episodes (crises) happen
It is not known if ADAKVEO is safe and effective in children under 16 years of age.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about ADAKVEO?
ADAKVEO may cause serious side effects, including infusion reactions.
Infusion reactions. Infusion reactions may happen within 24 hours of receiving an infusion of ADAKVEO. Tell your health care provider right away if you get any of the following signs and symptoms of an infusion reaction:
- chills or shivering
- shortness of breath or wheezing
Your doctor or health care provider may monitor you for signs and symptoms of infusion reactions.
ADAKVEO may interfere with a blood test.
Tell your health care provider that you are receiving ADAKVEO before having any blood tests. ADAKVEO may interfere with a laboratory test to measure your platelet counts.
Before receiving ADAKVEO, tell your health care provider about all of your medical conditions, including if you
- are pregnant or plan to become pregnant. It is not known if ADAKVEO may harm your unborn baby
- are breastfeeding or plan to breastfeed. It is not known if ADAKVEO passes into your breast milk. You and your health care provider should decide the best way to feed your baby during treatment with ADAKVEO
Tell your health care provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
The most common side effects of ADAKVEO include:
These are not all of the possible side effects of ADAKVEO. For more information, ask your health care provider or pharmacist.
Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please see full Prescribing Information, including Patient Information.