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What Is a Sickle Cell Pain Crisis?
Pain crises in sickle cell disease
Every sickle cell pain crisis matters
Sickle cell pain crises are also known as pain crisis and are sudden and unpredictable episodes (crises) that can last, on average, 10 days.
Pain crises in the clinical trial were defined as painful episodes leading to a health care visit (emergency room [ER], clinic, hospital, or local physician visit).
The following health conditions were also considered pain crises if they led to a health care visit:
- Respiratory issues, or acute chest syndrome
- Reduced blood flow or cell trapping in the liver, or hepatic sequestration
- Reduced blood flow or cell trapping in the spleen, or splenic sequestration
- Prolonged erections, or priapism
The efficacy of ADAKVEO on chronic pain was not studied in SUSTAIN.
It's important to speak to your health care providers regularly about your condition. Between visits, keep track of each pain crisis you have, even the ones you manage at home.
