What is the most important information I should know about ADAKVEO?

ADAKVEO may cause serious side effects, including infusion reactions. Infusion reactions. Infusion reactions may happen within 24 hours of receivi...

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Approved Use:

ADAKVEO is used in people 16 years of age and older who have sickle cell disease to help reduce how often certain episodes (crises) happen. It is not known if ADAKVEO is safe and effective in children under 16 years of a...

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Pain crises in sickle cell disease

Pain crises, also known as "vaso-occlusive crises" [vey-soh uh-kloo-siv] or VOCs, in sickle cell disease are unpredictable, sudden, and intense episodes of pain (crises) that can last, on average, 10 days.

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Treatment with ADAKVEO

Discover how ADAKVEO may play a role in managing pain crises in sickle cell disease.


*Pain crises were defined as painful episodes leading to a health care visit (ER, clinic, hospital, or local physician visit). Results were based on 132 patients with sickle cell disease. The median is the number that is exactly in the middle of all results seen in the 1-year study.